Houston Fertility Center

POF: Future Help On the Horizon?

May 22, 2008 @ 02:17 PM — by Sonja Kristiansen, MD
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In my experience as a fertility specialist - and as a mother - by far one of the most traumatic diagnoses to render to a patient is one of POF, premature ovarian failure.

A POF diagnosis can ring with emotionally painful finality in a patient's mind. It means, in effect, premature menopause, sometimes as early as the woman's 20's. However, I am grateful to have alternatives to present in many cases. For many women with POF, the use of donor eggs with IVF can result in successful pregnancy.

Today there is even better news, even if only of the long-range type. Scientists have found more evidence of genetic connections to the incidence of POF. What this means is that the future may possibly hold a test that can tell very young women of their chance for having POF.

Presumably if a young woman with healthy eggs tests positive for the gene mutation, she could have her healthy existing egg cells retrieved and cryopreserved for later use.

I look forward to every additional opportunity I'm given for presenting a fulfilled future to women with POF.

Oocyte-specific gene mutations cause premature ovarian failure - Baylor College of Medicine