POF: Future Help On the Horizon? By Sonja Kristiansen, MD on May 22, 2008

In my experience as a fertility specialist - and as a mother - by far one of the most traumatic diagnoses to render to a patient is one of POF, premature ovarian failure.

A POF diagnosis can ring with emotionally painful finality in a patient's mind. It means, in effect, premature menopause, sometimes as early as the woman's 20's. However, I am grateful to have alternatives to present in many cases. For many women with POF, the use of donor eggs with IVF can result in successful pregnancy.

Today there is even better news, even if only of the long-range type. Scientists have found more evidence of genetic connections to the incidence of POF. What this means is that the future may possibly hold a test that can tell very young women of their chance for having POF.

Presumably if a young woman with healthy eggs tests positive for the gene mutation, she could have her healthy existing egg cells retrieved and cryopreserved for later use.

I look forward to every additional opportunity I'm given for presenting a fulfilled future to women with POF.

Oocyte-specific gene mutations cause premature ovarian failure - Baylor College of Medicine

Dr. Sonja Kristiansen

Houston Fertility Center

Dr. Sonja Kristiansen is the founder and Medical Director of Houston Fertility Center. She is a board-certified Reproductive Endocrinologist Infertility (REI) specialist who is proud to help hopeful parents fulfill their dreams of having children. Our center is affiliated with the:

  • American College of Obstetricians and Gynecologists
  • American Society for Reproductive Medicine
  • Texas Medical Association

We provide convenient care for patients from greater Houston and visitors from out of town. For more information about our services, contact our office online or call (713) 225-5375 today.

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